CYCLAMIC ACID (N-CYCLOHEXYLSULFAMIC ACID)

CYCLAMIC ACID
PRODUCT IDENTIFICATION
CAS NO.	100-88-9
EINECS NO.	202-898-1
FORMULA	C₆H₁₃NO₃S
MOL WT.	179.23
H.S. CODE
TOXICITY
SYNONYMS	N-Cyclohexylsulfamic acid;
Cyclohexylsulfamate; Cyclohexylsulfamic acid; Sucaryl;
SMILES
CLASSIFICATION
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE	white crystals
MELTING POINT	165 - 170 C (Decomposes)
BOILING POINT
SPECIFIC GRAVITY
SOLUBILITY IN WATER	Soluble
SOLVENT SOLUBILITY
pH
VAPOR DENSITY
REFRACTIVE INDEX
NFPA RATINGS	Health: 1 ; Flammability: 0 ; Reactivity: 0
AUTOIGNITION
FLASH POINT
STABILITY	Stable under normal conditions.
GENERAL DESCRIPTION AND APPLICATIONS
Cyclamic Acid is a practically colourless, white crystalline powder with a sweet-sour taste. It and its salts (sodium and calcium) are used as a nonnutritive low-calorie sweetener choice ( but prohibited in some countries due to possible carcinogenic effects of its metabolic products). It is soluble in water and in ethanol. It is known about 40 times sweeter than sucrose.
SALES SPECIFICATION (NF-13, BP93)
APPEARANCE	white crystals
ASSAY	98.0% - 102.0% (anhydrous basis)
pH	5.5 - 7.0
CYCLOHEXYLAMINE	10ppnm max
DICYCLOHEXYLAMINE	1ppm max
ANILINE	1ppm max
As	3ppm max
Pb	1ppm max
Se	30ppm max
HEAVY MERALS	10ppm max
LOSS ON DRYING	1.0% max
TRANSPORTATION
PACKING	25kgs in drum
HAZARD CLASS
UN NO.
OTHER INFORMATION
`Hazard Symbols: XI, Risk Phrases: 22, Safety Phrases:`22-24/25
GENERAL DESCRIPTION OF CYCLOHEXANE
Cyclohexane is the six-membered alicyclic hydrocarbon consisting of six carbon atoms linked to each other to form a ring, with each carbon atom bearing two hydrogen atoms, C6H12. A cyclic compound is an organic compound that contains one or more closed rings of carbon atoms. The term alicyclic refers to cyclic compound that behaves chemically like aliphatic compounds (open-chain), which means the exclusion of carbocyclic compounds of aromatic rings with an array of ��-electrons characteristic. Cyclohexane is a colorless, highly flammable, mobile liquid with a pungent odor. It is insoluble in water and soluble in alcohol, ether, and almost organic solvents. Cyclohexane is a non-corrosive and quick volatilize liquid and sublimes between -5 to 5 C. Cyclohexane can exist in a number of interconvertible three-dimensional conformations, the two simplest being are the chair and boat conformation and others include the half-chair and twist-chair conformation. Cyclohexane can cause irritation to the eyes and mucous membranes in workers. Repeated and prolonged contact with skin may cause dermatitis. The substance has not been shown to cause the hematologic changes associated with exposure to benzene. Cyclohexane occurs naturally in crude oils. Some cyclohexane is recovered from petroleum streams by fractionation. The bulky commercial production of cyclohexane is based on hydrogenation of benzene in closed system. Cyclohexane consumption is linked almost entirely to nylon production. Nylon is further processed into fibers for applications in carpeting, automobile tire cord, clothing, and other growing industrial fields. Cyclohexane is used as a solvent, oil extractant, paint and varnish remover, dry cleaning material, and in solid fuels. It has been used as a insecticide itself. Cyclohexane is used as a chemical intermediate to produce target molecules. Natural compounds of one to five alicyclic rings with great variety and complexity are found particularly in steroids and terpenes. Cyclohexane structure, six membered-ring, is one of the major skeleton in nature. Cyclohexane derivatives can be used for the synthesis of pharmaceuticals, dyes, herbicides, plant growth regulator, plasticizers, rubber chemicals, cycloamines and other organic compounds.